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In clinical practice, however, physicians often prescribe medications for unlabeled (“off-label”) uses when published clinical studies, case reports, or their own clinical experiences support the efficacy and safety of those treatments. Physicians may use Valium outside its approved indications to treat social phobia, posttraumatic stress disorder, panic attacks, insomnia, premenstrual syndrome, and other conditions. As with other benzodiazepines, Valium is associated with dependence and abuse and is regulated as a controlled substance by state and federal laws. Valium’s effectiveness for treating anxiety may be explained by its pharmacological action in the brain at specific receptor sites. Receptors are specific sites on the nerve cell membrane that receive the signal from a neurochemical called the neurotransmitter. Once a neurotransmitter locks in on the receptor, the neurochemical signal is changed to an electrical or another chemical signal and travels down the neuron. The receptor sites in which benzodiazepines elicit their action are found in various regions of the brain, and the specific receptors are also known as benzodiazepine receptors. The coupled reaction of benzodiazepines to the receptors facilitates the inhibitory action of the neurotransmitter γ-aminobutyric acid (GABA) in that region of the brain. Benzodiazepines’ action on GABA receptors appears to produce their anxiolytic, sedative, and anticonvulsant actions. Valium, for example, is an effective anxiolytic, hypnotic (e.g., anaesthesia), and antiseizure medication.
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Dosage for VALIUM (diazepam) should be individualized for maximal beneficial effect. While the usual daily dosages given below will meet the needs of most patients, there will be some who may require higher doses. Lower doses are recommended for elderly and debilitated patients and patients with debilitating diseases. In the first few days of administration a cumulative effect of the drug may occur, and therefore, the dosage should be increased only after stabilization is apparent. The tablet can be divided into equal halves to facilitate dosing. The duration of treatment should be as short as possible. The patient should be reassessed regularly and the need for continued treatment evaluated, especially if the patient is symptom-free. It should not exceed 2 – 3 months, including the tapering-off period. Extension beyond this period should not take place without re-evaluation of the situation. It may be useful to inform the patient when treatment is started that it will be of limited duration and explain precisely how the dosage will be progressively decreased. Moreover, it is important that the patient be aware of the possibility of rebound phenomena, thereby minimizing anxiety over such symptoms, should they occur during withdrawal. There is evidence that, in the case of short-acting benzodiazepines, withdrawal phenomena can become manifest within the dosage interval, especially when the dosage is high. When long-acting benzodiazepines such as diazepam are being used, it is important to warn against changing to a short-acting benzodiazepine as withdrawal symptoms may develop.
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You can Buy Valium Pills Online here, but be aware that Valium comes with some side effects. You can Buy Valium Online Pills The most common side effects reported with Valium are sedation and drowsiness, especially shortly after initiating therapy. Other frequent symptoms are impaired concentration and memory, the feeling of dissociation (“spacey”), and impaired coordination.
Valium is contraindicated in patients with a known hypersensitivity to diazepam and, because of lack of sufficient clinical experience, in pediatric patients under 6 months of age. Valium is also contraindicated in patients with myasthenia gravis, severe respiratory insufficiency, severe hepatic· Children under six months of age due to lack of sufficient clinical experience.