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Dosage and Administration
Use the lowest effective dose for the patient. The recommended initial dose is 5 mg for women and either 5 or 10 mg for men, taken only once per night immediately before bedtime with at least 7–8 hours remaining before the planned time of awakening. If the 5 mg dose is not effective, the dose can be increased to 10 mg. In some patients, the higher morning blood levels following use of the 10 mg dose increase the risk of next day impairment of driving and other activities that require full alertness. The total dose of AMBIEN should not exceed 10 mg once daily immediately before bedtime. Ambien should be taken as a single dose and should not be readministered during the same night.
The recommended initial doses for women and men are different because zolpidem clearance is lower in women.
How to use
Since this medication takes effect quickly, take it by mouth immediately before bedtime on an empty stomach, or as directed by your doctor. Use this medication exactly as prescribed. Do not increase your dose, take it more frequently or use it for a longer period of time than prescribed because this drug can be habit-forming. If this drug is used for an extended period of time, do not suddenly stop using it without your doctor’s approval. Some conditions may become worse when the drug is abruptly stopped. Your dose may need to be gradually decreased. When used for an extended period, this medication may not work as well and may require different dosing. Talk to your doctor if this medication stops working well. You may experience trouble sleeping the first few nights after you stop taking this medication. This is called rebound insomnia and it is normal. It will usually go away after 1-2 nights. If this effect continues, contact your doctor. Read the Patient Information Leaflet available from your pharmacist. Inform your doctor if your condition persists or worsens.
Daytime drowsiness, dizziness, lightheadedness, constipation, diarrhoea, and dry mouth may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Although unlikely, this drug can infrequently cause memory loss. To avoid this effect, do not take a dose of this drug unless you have time for a full night’s sleep that lasts at least 7-8 hours. Tell your doctor immediately if any of these unlikely but serious side effects occur: fast/pounding heartbeat, unusual tiredness, new or worsening depression (rarely including thoughts of suicide), mental/mood changes, unsteadiness. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: chest pain. A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
Before taking zolpidem, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, depression, drug or alcohol dependency, lung/breathing problems (e.g., chronic obstructive pulmonary disease-COPD, sleep apnea). This drug may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. Avoid alcoholic beverages because they may increase the risk of this drug’s side effects. To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position. Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, which may lead to an increased risk of falling. This medication should be used during pregnancy only if clearly needed. Discuss the risks and benefits with your doctor. A small amount of this medication passes into breast milk. Consult your doctor before breastfeeding.